منابع مشابه
Modeling-Enabled Systems Nutritional Immunology
This review highlights the fundamental role of nutrition in the maintenance of health, the immune response, and disease prevention. Emerging global mechanistic insights in the field of nutritional immunology cannot be gained through reductionist methods alone or by analyzing a single nutrient at a time. We propose to investigate nutritional immunology as a massively interacting system of interc...
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A complete understanding of the immune system will ultimately require an integrated perspective on how genetic and epigenetic entities work together to produce the range of physiologic and pathologic behaviors characteristic of immune function. The immune network encompasses all of the connections and regulatory associations between individual cells and the sum of interactions between gene prod...
متن کاملImmunological Genome Project and systems immunology.
Immunological studies of single proteins in a single cell type have been complemented in recent years by larger studies, enabled by emerging high-throughput technologies. This trend has recently been exemplified by the discovery of gene networks controlling regulatory and effector αβ T cell subset development and human hematopoiesis. The Immunological Genome Project (ImmGen) aims to decipher th...
متن کاملEcological immunology of bird-ectoparasite systems.
Ecological immunology is a rapidly expanding field of research that attempts to explain variation in immune function across individuals, populations and species. Birds and ectoparasitic arthropods have frequently been used in attempts to measure the cost of immune function in relation to adult condition, nestling growth and other life history challenges. Unfortunately, most studies in ecologica...
متن کاملOntology development for biological systems: immunology
UNLABELLED We recently implemented improvements to the representation of immunology content of the biological process branch of the Gene Ontology (GO). The aims of the revision were to provide a comprehensive representation of immunological processes and to improve the organization of immunology related terms in the GO to match current concepts in the field of immunology. With these improvement...
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ژورنال
عنوان ژورنال: Current Opinion in Immunology
سال: 2020
ISSN: 0952-7915
DOI: 10.1016/j.coi.2020.06.006